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Francisco Liriano spoiled Kevin Youkilis' first game with Chicago, throwing a season-high seven innings to lead the Minnesota Twins to a 4-1 victory over the White Sox on Monday night.

Making his first start against the rival White Sox since his no-hitter in Chicago nearly 14 months ago, Liriano (2-7) allowed just three singles, two walks and a double. The left-hander struck out five, winning for the first time this month while holding the White Sox without a run until Alexei Ramirez's sacrifice fly in the seventh.

Jared Burton notched the save for the second straight game for the Twins, filling in for injured closer Matt Capps.